5 Top Emerging Startups Tackling Neurodegenerative Diseases

We analyzed 340 startups tackling neurogenerative diseases. Darmiyan, ClearSky Medical Diagnostics, Talisman, Voyager Therapeutics, and CogniHealth develop 5 top solutions. Learn more in our Global Startup Heat Map!

Our Innovation Analysts recently looked into emerging technologies and up-and-coming startups working on solutions for the healthcare sector. As there is a large number of startups working on a wide variety of solutions, we want to share our insights with you. This time, we are taking a look at 5 promising startups tackling neurodegenerative disease through technology.

Heat Map: 5 Top Emerging Startups Tackling Neurodegenerative Diseases

Using our StartUs Insights Platform, covering 1.116.000+ startups & emerging companies, we looked at innovation in the healthcare sector. For this research, we identified 340 relevant solutions and picked 5 to showcase below. These companies were chosen based on a data-driven startup scouting approach, taking into account factors such as location, founding year, and technology among others. Depending on your specific criteria, the top picks might look entirely different.

The Global Startup Heat Map below highlights 5 startups & emerging companies developing innovative solutions to tackle neurodegenerative diseases. Moreover, the Heat Map reveals regions that observe a high startup activity and illustrates the geographic distribution of all 340 companies we analyzed for this specific topic.


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Which startups develop the other 335 solutions?


Darmiyan – Image Analytics

Alzheimer’s disease (AD) is a degenerative brain disease that causes a continuous decline in thinking, behavioral, and social skills and disrupts a person’s ability to function independently. Early diagnosis of this neurodegenerative disease increases a patient’s chances of benefitting from treatment. Software-enabled detection of neurodegenerative changes from medical images is an innovative solution for the early diagnosis of AD.

Darmiyan is a US-based startup that develops an image analytics software for early detection and monitoring of AD and other neurodegenerative disorders. The solution analyzes magnetic resonance imaging (MRI) scans. It detects and quantifies degenerative changes in brain tissue at the cellular level in every voxel, a three dimensional (3D) pixel, of a brain MRI scan.

ClearSky Medical Diagnostics – Diagnosis & Monitoring

As the populations in developed countries age, the world faces an epidemic of aging-related diseases. These include debilitating neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease. Startups around the world are developing medical devices to monitor the progress of such diseases to help healthcare providers in fighting this epidemic.

ClearSky Medical Diagnostics is a UK-based startup that specializes in medical devices for the diagnosis & monitoring of neurodegenerative diseases. The company’s portfolio includes solutions for at-home dyskinesia monitoring, smart gloves for differential diagnostics of neurodegenerative diseases, patient visuospatial ability assessment, and Parkinson’s symptom monitoring. These devices provide instant feedback to make neurodegenerative disease management easier.

Talisman Therapeutics – Stem Cell Therapy

Worldwide, approximately 50 million people suffer from Alzheimer’s disease and other dementias. AD is one of the most common causes of disability in elderly people. It constitutes an enormous social and economic burden for the society and, in particular, for the family members of AD patients. To ease this burden, companies are exploring novel technologies and therapies, such as stem cell therapy.

Talisman Therapeutics is a UK-based company that uses stem cell-based models to discover treatments for AD. The 2D, 3D, and co-culture models are optimized for high-content and high-throughput analysis. Using these models in the drug discovery process enables the company to identify disease-modifying and more therapeutically relevant compounds.

Voyager Therapeutics – Gene Therapy

Millions of people worldwide suffer from neurodegenerative diseases. As the disease progresses, the degeneration of the neurons leads to cognitive impairment, motor dysfunction, loss of decision making, and other severe consequences. Gene therapy has the potential to help people suffering from neurodegenerative diseases through several approaches.

Voyager Therapeutics is a US-based clinical-stage gene therapy company that develops treatments for neurodegenerative diseases. Its pipeline includes therapies for the treatment of Alzheimer’s, Huntington’s, Parkinson’s disease, and Friedreich’s ataxia. Depending on the disease, the company’s therapies use different gene therapy solutions, such as gene replacement, gene knockdown, or vectorized antibody approach.

CogniHealth – Care Guidance

Among neurodegenerative diseases, dementias are one of the leading medical and societal challenges, particularly in the aging European Union population. As the population ages, the impact of these diseases is expected to increase. Care guidance apps support caregivers in looking after patients suffering from dementia.

Scotland-based startup CogniHealth develops CogniCare, an app for family members of people suffering from dementia. The app supports caregivers by providing advice and resources to help with daily tasks. It also provides advice on self-care to help carers reduce stress and improve wellbeing.

What About The Other 335 Solutions?

While we believe data is key to creating insights it can be easy to be overwhelmed by it. Our ambition is to create a comprehensive overview and provide actionable innovation intelligence so you can achieve your goals faster. The 5 startups showcased above are promising examples out of 340 we analyzed for this article. To identify the most relevant solutions based on your specific criteria, get in touch.

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