Microbiome cosmetic products are gaining traction as consumers and companies shift toward skin care that supports the skin’s natural ecosystem. The top microbiome skincare companies are driving innovation in this space by developing formulations that balance, protect, and enhance the skin microbiome. These companies combine biotechnology, dermatology, and personalized care to create products that go beyond traditional cosmetics.
In this article, we spotlight 10 emerging startups offering microbiome cosmetic products that are shaping the future of skin health. Selected for their innovation, science, and market fit, these startups show how microbiome solutions are reshaping personal care into a more targeted, skin-friendly approach.
Global Startup Heat Map highlights Emerging Startups Offering Microbiome Products
Through the Big Data & Artificial Intelligence (AI)-powered StartUs Insights Discovery Platform, covering over 7M+ startups, 20K+ technology trends plus 150M+ patents, news articles & market reports, we identified 10 startups offering microbiome cosmetic products.
The Global Startup Heat Map below highlights the 10 microbiome cosmetic companies you should watch in 2025 as well as the geo-distribution of 80+ microbiome cosmetic startups & scaleups we analyzed for this research.
According to our data, we observe high startup activity in the USA and the UK, followed by India. The top 5 Startup Hubs for microbiome cosmetic products are London, New York City, Singapore, San Francisco, and San Francisco.
Meet Emerging Startups Offering Microbiome Cosmetic Products in 2025
We hand-picked startups to showcase in this report by filtering for their technology, founding year, location, funding, and other metrics. These 10 microbiome skincare brands work on solutions ranging from microbiome-smart ingredients and enzyme technology to selective bacterial targeting and natural pigments from microbial sources.
- Phiome – Microbiome Smart Ingredients
- BYOME LABS – AI-powered Microbiome Measurement Tests
- Glacies Biome – Personalized Microbiome Skincare
- mmmico eats – Microbial Extract through Fermentation Technology
- Iniya Bioprobes – Natural Pigments from Microbial Sources
- Ownia Cosmetics – Microbiome Technology Skincare
- BIOTALIFE – Skin Microbiome Real-life Diagnoses
- ArrowBiome – Highly-selective Bacterial Targeting
- Topaz Biosciences – Enzyme Technology
- ResVita Bio – Bio-engineered Skin Bacteria
1. Phiome
- Founding Year: 2024
- Location: Ghent, Belgium
- Use For: Microbiome-Smart Ingredients
Phiome specializes in body odour preventative technology using microbiome-smart ingredients that modify skin bacterial composition. Its technology uses probiotic and prebiotic components to increase beneficial and pleasant-smelling bacteria. While the technology is reducing odour-associated taxa such as Corynebacterium spp and Staphylococcus hominis spp.
Moreover, the microbiome-smart ingredients activate on contact with skin moisture, which then integrate into cosmetics and performance textiles. Further, these ingredients enable cell renewal and strengthen the skin’s immune response. By focusing on microbial balance, Phiome provides a biological solution that aligns with sustainable and microbiome-friendly product development.
2. BYOME LABS
- Founding Year: 2023
- Location: Le Coudray, France
- Use For: AI-powered Microbiome Measurement Tests
BYOME LABS performs AI-powered microbiome measurement tests for cosmetics brands to deploy at the point of sale. The AI system uses a rapid antigen-style test to analyze skin parameters through a simple swab.
Additionally, the integrated AI interprets the results and recommends products aligned with the consumer’s microbiome profile. This solution supports multiple categories including skincare, scalp care, oral care, and vaginal health.
Further, BYOME LABS allows brands to reduce product returns and improve customer satisfaction by aligning product offerings with individual skin compatibility.
3. Glacies Biome
- Founding Year: 2024
- Location: Luxembourg, Luxembourg
- Use For: Personalized Microbiome Skincare
Glacies Biome utilizes advanced AI models and sequencing of the facial microbiome to create highly personalized skincare. It provides a centralized platform for skincare professionals to easily collect and manage diagnostics, treatment plans, and analytical data. The startup also allows for diagnosis, restoration, and prevention of aging by addressing the unique needs of each individual’s skin.
4. mmmico eats
- Founding Year: 2023
- Location: Sevilla, Spain
- Use For: Microbial Extract through Fermentation Technology
mmmico eats utilize fermentation technology to develop a potent microbial extract made of astaxanthin and other carotenoids. This product consists of high antioxidant properties and colorant, thereby improving food, nutraceutical, cosmetic, and animal feed formulations.
The startup uses a bioinformatics platform that analyzes microbial genomes to identify and optimize strains for targeted compound production. Moreover, it produces high-yield, high-functionality ingredients in reduced timeframes. The startup also provides a sustainable alternative to synthetic additives by combining microbial engineering with data-driven development.
5. Iniya Bioprobes
- Founding Year: 2023
- Location: Mysuru, India
- Use For: Natural Pigments from Microbial Sources
Iniya Bioprobes produces natural pigments from microbial sources. It utilizes CRISPR-based genome engineering, microbial fermentation, and protein engineering to increase pigment yield and process efficiency.
Further, the startup produces high-quality pigments as alternatives to synthetic dyes. These pigments are suitable for applications in food, cosmetics, pharmaceuticals, and textiles. Iniya Bioprobes ensures that the production processes are sustainable, minimize waste, and environmental impact for industries.
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6. Ownia Cosmetics
- Founding Year: 2022
- Location: Madrid, Spain
- Use For: Microbiome Technology Skincare
Ownia Cosmetics develops microbiome-based skincare products to protect the skin’s natural barrier. It uses prebiotics such as oat extract or chicory root inulin. This promotes the growth of beneficial bacteria, and postbiotics like Lactococcus ferment lysate or lactic acid to stabilize the skin’s microbiome.
Additionally, this microbiome-based skincare product regulates skin pH, reduces inflammation, and protects against harmful pathogens. Further, the products target dysbiosis-related conditions, including acne, rosacea, and atopic dermatitis.
7. BIOTALIFE
- Founding Year: 2022
- Location: Buenos Aires, Argentina
- Use For: Skin Microbiome Real-life Diagnoses
BIOTALIFE provides skin microbiome real-life diagnoses for businesses in the skincare and health sectors. It enables non-invasive sampling through dermatologist-administered swabs, DNA extraction and sequencing in a laboratory setting.
Moreover, the startup utilizes a proprietary microbiome database and predictive artificial intelligence to identify microbial compositions, assess skin health, and recommend tailored interventions. These insights allow businesses to integrate microbiome-based customization into their offering.
8. ArrowBiome
- Founding Year: 2022
- Location: Singapore
- Use For: Highly-selective Bacterial Targeting
- Funding: Raised USD 1 million in Seed funding
ArrowBiome develops a platform for selective bacterial targeting in the human microbiome. It uses patented technology to remove specific bacterial strains while leaving beneficial microbes intact.
The platform applies to product development in areas such as acne, body odour, gut health, and antimicrobial resistance. Further, the startup enables precise bacterial management to support differentiated applications in consumer and clinical settings.
9. Topaz Biosciences
- Founding Year: 2022
- Location: Emeryville, USA
- Use For: Enzyme Technology
Topaz Biosciences utilizes enzyme-based technology for skin care product formulations. It applies protein scaffolds derived from nature to reduce harmful skin bacteria linked to conditions such as eczema and acne.
Moreover, the startup uses a metagenomics platform to access microbial diversity and identify enzymes with targeted activity. Topaz Biosciences further enables product developers to incorporate microbiome-focused functionality into skin care formulations using biologically sourced components.
10. ResVita Bio
- Founding Year: 2021
- Location: Berkeley, USA
- Use For: Engineered Skin Bacteria
- Funding: Awarded a USD 2 million Phase II SBIR Grant
ResVita Bio engineers skin bacteria to deliver therapeutic proteins directly to affected skin areas. Its platform uses synthetic biology to create inert bacterial strains that act as localized protein delivery systems. The continuous protein therapy enables sustained and targeted treatment with limited systemic exposure.
Moreover, the platform addresses conditions such as Netherton syndrome and atopic dermatitis. ResVita Bio further allows pharmaceutical and biotech companies to develop microbiome-based skin therapies.
Discover All Emerging Cosmetics Startups
The cosmetics startups showcased in this report are only a small sample of all startups we identified through our data-driven startup scouting approach. Download our free Cosmetics Innovation Report for a broad overview of the industry or get in touch for quick & exhaustive research on the latest technologies & emerging solutions that will impact your company in 2025!
