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Single use technology companies are reshaping healthcare, biotech, and pharmaceutical manufacturing with sterile and disposable solutions. In 2025, startups driving this shift are addressing key industry needs, from reducing cross-contamination risks to innovating bioprocessing and patient care. This article spotlights 10 promising companies innovating across areas like single-use urological devices, electrocautery tools, micro-batch reactors, and more.
This list is essential for innovators, manufacturers, R&D teams, procurement leaders, and investors looking to identify high-potential players and trends in single-use technologies.
Global Startup Heat Map highlights Emerging Single Use Technology Companies to Watch
Through the Big Data & Artificial Intelligence (AI)-powered StartUs Insights Discovery Platform, covering over 7M+ startups, 20K+ technology trends plus 150M+ patents, news articles & market reports, we identified 140+ single-use technology startups.
The Global Startup Heat Map below highlights emerging single-use technology startups you should watch in 2025, as well as the geo-distribution of 140+ single-use technology startups & scaleups we analyzed for this research.
According to our data, we observe high startup activity in the US and India, followed by the UK. The top 5 Startup Hubs for single-use technology companies are London, Bangalore, New York City, San Francisco, and Hyderabad.
Discover Emerging Single Use Technology Companies to Watch in 2025
We hand-picked startups to showcase in this report by filtering for their technology, founding year, location, funding, and other metrics. These 10 single use technology startups work on solutions ranging from sustainable medical devices and single use urological solution to single use programs and electrocautery device.
- aaruni lifesciences – Bioprocessing Equipment and Consumables
- Porrima Technologies – Sustainable Medical Devices
- ReelReactor – Continuous Micro-batch Reactor
- InSpek – Bio Process Monitoring with Integrated Photonic Sensors
- Single Pass – Electrocautery Device
- Aulea Medical – Single Use Urological Solution
- BioPulse Solutions – Custom Biopharma Solutions Platform
- INTO Bioprocess – Custom Made Single-use Solutions
- Bioscibex – Single-use Bioreactor Solutions
- Fastnet bio – Single Use Programs
1. aaruni lifesciences
- Founding Year: 2021
- Location: Bangalore, India
- Use For: Bioprocessing Equipment and Consumables
Aaruni Lifesciences develops bioprocessing tools and supplies, such as disposable bioreactors, chromatography systems, and filtering solutions.
Its single-use technology uses pre-sterilized, disposable parts like bioreactors, bags, and filters to expedite cell culture and bioprocessing. This eliminates the need for cleaning and sterilizing in between production cycles.
Additionally, the technology supports flexible and economical manufacturing by using less water and energy. This reduces the risk of cross-contamination, and speeds up setup times.
The Ulba series encompasses a range of single-use systems for fluid handling. Vrddhi focuses on bioreactor technologies catering to various scales and applications. Shuddhi represents the startup offerings for purity and precision in bioprocessing.
Moreover, ValTer provides strength and protection in filtration. It also offers components such as cartridges and capsules, tyvek sheets, media bottles and petri dishes.
Further, Samyama is the proprietary software platform that offers businesses with open architecture and customizable workflows.
2. Porrima Technologies
- Founding Year: 2023
- Location: Sydney, Canada
- Use For: Sustainable Medical Devices
Porrima Technologies provides biodegradable, single-use medical equipment. This includes syringes, blood collection tubes, IV bags, and blood bags for the healthcare sector.
Moreover, the startup utilises its patented biodegradable polymers that spontaneously break down after usage. These products ensure drug compatibility and patient safety throughout clinical applications.
Its products meet strict industry standards for quality while promoting environmental sustainability. It does so by lowering the ecological impact of medical procedures and eliminating plastic waste.
The startup also combines research-driven design and production to provide solutions that support environmental stewardship and patient care.
Porrima Technologies supports environmentally friendly practices in the medical industry by offering healthcare providers safe, sustainable, and efficient substitutes for traditional single-use medical devices.
3. ReelReactor
- Founding Year: 2022
- Location: Boise, Idaho, USA
- Use For: Continuous Micro-batch Reactor
ReelReactor offers the continuous micro-batch reactor which is called as ReelReactor. It is a sterile, single-use consumable for the production of pharmaceuticals and biologics. The reactor feeds reactants into a disposable chamber and mixes at precise ratios for uniformity. This enables simultaneous processing of multiple micro-batches at different stages.
Each micro-batch then reacts in flow and exits the consumable upon completion. This method solves inconsistency and inefficiency issues present in conventional batch and continuous stirred-tank reactors. It also eliminates the need for cleaning, reduces downtime, and ensures that every drop of product keeps the same formulation and reaction time.
The automated, small setup requires less space and manpower, and the single-use consumable design reduces the risk of cross-contamination and facilitates rapid changeover.
Further, the reactor enables pharma producers to meet the increasing demand for high-quality therapies utilising the scalable, economical, and reliable production.
4. InSpek
- Founding Year: 2021
- Location: Suresnes, France
- Use For: Bio Process Monitoring with Integrated Photonic Sensors
- Funding: InSpek raises EUR 6 million in funding from seed round and EIC grant
InSpek creates integrated photonic sensors for real-time bio process monitoring in pharmaceutical and biomanufacturing settings.
Its sensors enable accurate monitoring of molecular composition and key factors such as cell growth, nutrition levels, and metabolic activity directly within bioreactors or process lines. This is achieved by fusing photonic integrated circuits (PICs) with established optical techniques like Raman spectroscopy.
Additionally, the sensors work by passing light through a tiny, all-in-one probe. This probe uses light scattering to identify changes in the process medium and provides data without the need for human sampling.
The sensors feature the capacity to monitor several parameters on a single chip. They are also resilient which makes them suitable for use in hazardous or space-constrained locations.
InSpek’s photonic sensors further enable engineers to optimize production, minimize waste, and gain more control over intricate bioprocesses by providing precise and ongoing knowledge.
5. Single Pass
- Founding Year: 2021
- Location: Lake Forest, California, USA
- Use For: Electrocautery Device
Single Pass provides the Kronos electrocautery device. It is a battery-operated, one-time-use instrument for effectively sealing biopsy channels following solid organ surgeries.
The device works by passing a heated probe via the biopsy guide needle, which can reach temperatures of up to 90°C. This cauterises tissue and achieves immediate hemostasis in the biopsy tract..
Moreover, the device allows clinicians to completely close the channel and use larger needles for obtaining tissue samples in fewer passes. Its integrated depth gauge and customizable design ensure exact alignment with a range of needle lengths.
The device further offers ease of use, portability, and eliminates the need for additional hemostatic agents, medications, or extended post-procedure observation. Single Pass improves patient safety and allwos medical professionals produce biopsy results by reducing bleeding risks and procedure expenses.
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6. Aulea Medical
- Founding Year: 2023
- Location: Pleasanton, California, USA
- Use For: Single Use Urological Solution
Aulea Medical offers a single-use urological solution which is Veloxion resectoscope. It is a single-use all-in-one endoscopic resection device. It simplifies operations for ailments like enlarged prostates and bladder tumors. The device combines essential surgical tasks like resection, fluid control, irrigation, and aspiration.
Additionally, Aulea Medical ensures consistent performance and minimizes cross-contamination hazards by using a new device for every patient. It supports safe and effective tissue removal by automatic chip and fluid evacuation with integrated pressure management.
Further, the device reduces surgery times, minimizes postoperative hospitalization, and improves clinician efficiency. It eliminates the need for complicated setups and equipment sterilization.
Aulea Medical also advances safety and efficiency in single-use technologies for the pharmaceutical industry while providing a patient-focused approach to urological operations.
7. BioPulse Solutions
- Founding Year: 2022
- Location: Hyderabad, India
- Use For: Custom Biopharma Solutions Platform
- Notable News: BioPulse Solutions holds a valuation of INR 360 million
BioPulse Solutions provides a customized biopharma solutions platform that combines single-use technologies and engineered products for the biopharmaceutical market.
Its BioPulse TOOLBox allows businesses to design and configure precision assemblies. This involves hose assemblies, tubing assemblies, and 2D/3D bags, customised to specific process requirements.
Additionally, the platform facilitates the smooth integration of single-use components like tubing, connectors, filters, and containment bags. The startup’s open architecture offers flexibility and optimization for upstream, downstream, lab, and fill-finish applications by combining technologies from various solutions.
It offers features like a do-it-yourself configurator for quick prototyping, certified cleanroom manufacturing. The platform also features value-added services for technical support, documentation, and validation.
BioPulse Solutions further enables biopharma manufacturers to improve process control, lower contamination risk, and speed up drug development. It is achieved by providing scalable, effective, and customizable fluid handling and single-use systems.
8. INTO Bioprocess
- Founding Year: 2022
- Location: Vilniaus, Lithuania
- Use For: Custom Made Single-use Solutions
INTO Bioprocess develops custom made single-use solutions for biotechnology, biopharma, and pharma applications. It offers products such as INTO Single-Use Assemblies and INTO Single-Use Bags to streamline and simplify bioprocessing workflows.
Moreover, The products replace conventional multi-use components in processes like filling, filtration, sampling, and waste collection with single-use assemblies. These assemblies come preassembled and ready for instant integration, eliminating the need for cleaning or sterilizing. It also speeds up batch turnaround.
INTO Single-Use Bags offer safe biopharmaceutical fluid handling and are customizable in terms of volume, shape, and connection type to meet individual process requirements. These are made from multilayer polyethylene/ethylene-vinyl alcohol/polyethylene (PE/EVOH/PE) barrier films.
The startup’s solutions further improves process flexibility, facilitate quick product changes, and lower the risk of contamination. Its ready-to-use chemical storage components also avoid complicated in-house preparation.
9. Bioscibex
- Founding Year: 2024
- Location: Monthey, Switzerland
- Use For: Single-use Bioreactor Solutions
- Funding: Bioscibex secured funding of CHF 40K
Bioscibex provides single-use bioreactor solutions that automate and optimize cell culture for the production of biologics and cell therapies.
Its single-use bioreactor operates as a fully closed, automated system. It accommodates volumes from 30 mL to 30 L in the same vessel, enabling simplified cell expansion from vial thawing to large-scale production without manual transfers.
Moreover, the bioreactor incorporates advanced sensors for dissolved oxygen, pH, pCO₂, and capacitance-based cell counting to provide real-time monitoring and accurate control of crucial process parameters.
Its features include a system that minimizes contamination risk and product loss by reducing the number of process steps from seven to two. It also offers a 1000:1 turndown ratio for high scalability, along with a modular architecture that allows for process modification.
Bioscibex further enables manufacturers to improve drug development and deliver high-quality medicines by streamlining processes, decreasing cleanroom requirements, and reducing costs.
10. Fastnet bio
- Founding Year: 2022
- Location: Belmont, Massachusetts, USA
- Use For: Single Use Programs
Fastnet bio provides the biopharmaceutical industry with GMP-compliant single-use programs that cover design, qualification, supply chain optimization, and sustainability.
The startup integrates process and equipment design, material standardization, and vendor qualification. This provides customized single-use technology solutions to ensure smooth project delivery from conception to implementation.
Its programs enable clients to lower operating costs and expedite technology transfers. It also supports regulatory compliance through risk assessment, extractables and leachables qualification, and strong supply chain management.
It further provides a platform-based strategy, the development of single-use technology libraries, support for dual sourcing, and sustainability evaluation.
Fastnet Bio allows clients to achieve faster speed-to-market, streamlined operations, and enhanced quality by centralizing project information and streamlining material selection.
Discover All Emerging Pharma Startups
The pharma startups showcased in this report are only a small sample of all startups we identified through our data-driven startup scouting approach. Download our free Pharma Innovation Report for a broad overview of the industry or get in touch for quick & exhaustive research on the latest technologies & emerging solutions that will impact your company in 2025!
