This article features 10 new stem cell therapy companies advancing treatments with the latest technologies. These companies present solutions ranging from unwanted cell removal systems and managing erectile dysfunction to chronic spinal cord injury therapies. Highlighting the growth in the sector, each company provides distinct advancements, contributing to modern medicine and patient care.
Continue reading to gain up-to-date and data-driven insights on:
- Profiles of 10 Emerging Stem Cell Therapy Companies
- How to Scout the Best Stem Cell Therapy Companies Easily
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Key Takeaways
Drawing insights from the Big Data & AI-powered StartUs Insights Discovery Platform that provides data on over 4.7+ million emerging companies globally, we explore the evolving landscape of the stem cell therapy industry. This sector is marked by key trends and a substantial workforce, shaping its future. The last time we updated this report was 5 days ago. If there’s something missing or off, your tips are welcome! Here are some key insights at a glance:
- Latest Stem Cell Therapy Trends: The latest stem cell therapy trends include biomedicine, stem cell differentiation, cryopreservation, immunotherapy, and tumor microenvironment.
- Stem Cell Therapy Industry Statistics: The global stem cell therapy industry encompasses 5.6K+ organizations and has about 284.3K workforce. It is experiencing a dip of 0.33% in annual growth rate but has seen the emergence of 300+ new stem cell therapy companies in the past five years. On average, each of these 300+ new companies employs about 27 people.
- 10 New Stem Cell Therapy Companies to Watch:
- Plurify – Unwanted Cell Removal
- Blue Cell Therapeutics – Erectile Dysfunction Therapy
- YJ Cerapeutics – Chronic Spinal Cord Injuries Therapy
- Progenicyte Therapeutics – Neurodegenerative & Cognitive Therapies
- ConductiveBio – Neural Implant Designing
- Immugenia – Chimeric Antigen Receptor (CAR) therapies
- StemSight – Corneal Blindness Treatment
- EXO Biologics – Exosome-based Therapies
- ActiTrexx – Inflammatory Condition Reduction
- Noga Therapeutics – Blood Stem Cell Reprogramming
Meet 10 out of 300+ New Stem Cell Therapy Companies
In this section, we explore 10 top stem cell therapy companies that reshape the healthcare landscape. They innovate with CAR therapies that reduce inflammation associated with chronic conditions, reprogramming blood stem cells & more. Their work increases the efficacy of precise cellular interventions in modifying disease trajectories in clinical settings.
Note on Signal Strength
One of the unique metrics we feature for each company is Signal Strength, a proprietary data point generated by our Discovery Platform. It gauges the extent to which a company’s influence has permeated the global ecosystem of startups, scaleups, and emerging companies. This proprietary metric serves as a valuable guidepost for understanding a company’s standing in the broader market landscape.
1. Plurify
- Founding Year: 2024
- Employee Range: 2-10
- Location: UK
- Signal Strength: Medium
- What they do: Plurify’s purification process enhances stem cell therapy. In the first stage, the company uses deep analytics to identify and target unwanted cells within stem cell products. Plurify also designs a component to eliminate these impurities to ensure a safer and higher-quality cell therapy solution.
2. Blue Cell Therapeutics
- Founding Year: 2019
- Employee Range: 11-50
- Location: Denmark
- Signal Strength: Strong
- What they do: Blue Cell Therapeutics uses blue cell therapy for treating erectile dysfunction. It promotes angiogenesis and repairs endothelium, vascular smooth muscles, and neurons while inhibiting inflammation. Leveraging advanced isolation and culture techniques, the company produces a homogenous, potent stem cell population from adipose tissue. These stem cells exhibit improved angiogenic capabilities, eliminating the need for liposuction.
3. YJ Cerapeutics
- Founding Year: 2021
- Employee Range: 2-10
- Location: South Korea
- Signal Strength: Medium
- What they do: YJ Cerapeutics develops neural stem cells (ciNSC) using small molecule compounds for treating chronic spinal cord injuries. The mesenchymal stem cells (MSCs), derived from umbilical cord blood, adipocytes, or bone marrow differentiates into various cell types like adipocytes, osteoblasts, and chondrocytes. These MSCs undergo direct conversion into ciNSCs through the application of small molecules. Moreover, this high efficiency and low cost approach eliminates the problems associated with induced pluripotent stem cells and embryonic stem cells.
4. Progenicyte Therapeutics
- Founding Year: 2022
- Employee Range: 2-10
- Location: USA
- Signal Strength: Medium
- What they do: Progenicyte Therapeutics makes KS217, a small molecular weight compound to increase endogenous stem cells. It pairs with phenserine in the company’s APC100 drug to increase neural stem cell activity and cognitive function. This combination of KS217 and APC100 addresses the challenges in treating cervical spinal cord injuries, stroke, Parkinson, amyotrophic lateral sclerosis (ALS), Alzheimer, and huntington. The company’s oral drugs also target neurodegenerative diseases and the compound offers applications for skin aging reversal, hair growth stimulation, and corneal regeneration.
5. ConductiveBio
- Founding Year: 2020
- Employee Range: 2-10
- Location: USA
- Signal Strength: Medium Strong
- What they do: ConductiveBio combines stem cell therapy and electric simulations to design a neural implant. It develops a conductive bioscaffold that utilizes nanomaterials to facilitate cell transplantation. It also incorporates an electrical circuit and a cell receptive layer to deliver electrical, biochemical, and topological cues for cell attachment and differentiation. Further, the bioscaffold supports tissue integration and regeneration by up-regulating genes associated with neurotrophic and signaling factors. This approach leverages the body’s natural healing processes to repair brain damage from stroke.
6. Immugenia
- Founding Year: 2020
- Employee Range: 1-10
- Location: Canada
- Signal Strength: Very Strong
- What they do: Immugenia utilizes hematopoietic stem cells (HSCs) to create CAR therapies for treating cancers. The company utilizes specific promoters for immune cell activity (SPICAs) to ensure gene expression in targeted cells. This selectivity eliminates the off-target effects of current chimeric antigen receptor T-cell (CAR-T cell) therapies. The HSCs self-renew and produce a constant supply of CAR-T and natural killer (NK) cells. This way, the therapy offers protection through CAR cell regeneration from HSCs and maintains vigilance against cancer relapse with ongoing T cell replenishment. Further, it mitigates common adverse effects such as cytokine release syndrome and benefits from HSCs’ resilience to chemotherapy.
7. StemSight
- Founding Year: 2021
- Employee Range: 2-10
- Location: Finland
- Signal Strength: Very Strong
- What they do: StemSight combines induced pluripotent stem cells (iPSCs) and functional biomaterials to treat corneal blindness. These cells self-renew and differentiate into various body cell types. They target limbal stem cell deficiency (LSCD) and make other types of corneal cells to treat blindnesses such as corneal endothelial dystrophies. This technology, in turn, replaces corneal tissue and eliminates the need for donor tissue.
8. EXO Biologics
- Founding Year: 2019
- Employee Range: 11-50
- Location: Belgium
- Signal Strength: Very Strong
- What they do: EXO Biologics produces exosome-based therapies for rare inflammatory diseases. The company’s drug candidate comprises therapeutic extracellular vesicles derived from cultured mesenchymal stromal cells. It offers relief for conditions like bronchopulmonary dysplasia in preterm infants. The exosomes deliver specific therapeutic agents directly to affected cells and organs. The company’s EXOB-001 product involves allogeneic extracellular vesicles that promote tissue repair and immune modulation. Additionally, EXO Biologics produces an automated production platform that loads therapeutic molecules to supply high-quality exosomes.
9. ActiTrexx
- Founding Year: 2020
- Employee Range: 11-50
- Location: Germany
- Signal Strength: Very Strong
- What they do: ActiTrexx offers Actileucel, a cell therapy that leverages activated regulatory T cells. These cells modulate immune responses to reduce the unwanted activation of CD4+ T lymphocytes. This lowers inflammatory reactions in conditions like graft-versus-host-disease (GvHD), solid organ transplantation, and autoimmune diseases.
10. Noga Therapeutics
- Founding Year: 2020
- Employee Range: 2-10
- Location: Israel
- Signal Strength: Very Strong
- What they do: Noga Therapeutics develops a non-invasive method to enrich stem cell populations by leveraging blood-stem-cell reprogramming. This method utilizes specific radio frequencies to target and activate the desired stem cells within a patient’s body with the company’s Cocoon manufacturing system. This system enhances precision and reproducibility and reduces the time for manufacturing genetically reprogramming stem cells using lentiviruses. Noga Therapeutics’ solution also facilitates the direct delivery of gene-based drugs to the brain by reprogramming macrophages to bypass the blood-brain barrier. This avoids extraction and manipulation of cells, making treatment more accessible and minimizing risks. The company’s gene therapy treats neurological conditions such as Parkinson’s and Alzheimer’s.
Quick Tip to Find New Stem Cell Therapy Companies
Utilizing a SaaS platform like the Discovery Platform for identifying new stem cell therapy companies provides significant benefits compared to traditional scouting methods:
- Streamlined Efficiency: The Discovery Platform offers advanced tools that streamline the scouting process. It replaces hours of your conventional desk research, saving time and resources in identifying stem cell therapy innovations.
- Access to Real-time Insights: Gain a competitive edge with up-to-date information on the latest trends in the stem cell therapy industry. The platform keeps you informed with near real-time updates on emerging stem cell therapy companies and news. This enables you to make swift and informed decisions.
- Tailored Exploration: Customize your search to focus on specific niches within the stem cell therapy sector, such as unwanted cell removal, exosome-based, or CAR therapies. The platform’s diverse filtering options allow you to target your scouting efforts precisely, ensuring that you find the most relevant and upcoming stem cell therapy solutions.
Ready to Explore All New Stem Cell Therapy Companies?
We’ve explored the dynamic landscape of the stem cell therapy industry, examining the latest trends and spotlighting exceptional companies driving innovation. To dive deeper, download our free Pharma Report or schedule a demo of the Discovery Platform for a customized exploration of these groundbreaking developments. Interested in enhancing our coverage of startups and tech? We value insights from experts like you – reach out!
