This article provides an analysis of 10 new bioengineering companies that innovate across several key areas of the industry. Some of these companies advance therapeutic molecule creation to leverage synthetic biology for precise cellular therapies. A few other companies develop sophisticated cell modeling techniques that enhance drug discovery and disease modeling accuracy. Each company showcases technologies that provide advancements in bioengineering applications.
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Key Takeaways
Drawing insights from the Big Data & AI-powered StartUs Insights Discovery Platform that provides data on over 4.7+ million emerging companies globally, we explore the evolving landscape of the bioengineering industry. This sector is marked by key trends and a substantial workforce, shaping its future. We updated this report 5 days ago. Noticed something’s off? Let’s make it right together — reach out! Here are some key insights at a glance:
- Current Bioengineering Trends: The current bioengineering trends include gene editing & modification, alternative proteins, regenerative medicine, tissue engineering, and personalized medicine.
- Bioengineering Industry Statistics: The global bioengineering industry includes 4.7K+ organizations and has a 15K workforce. It experienced an increase of 6.38% in annual growth rate over the past five years and has seen the emergence of 800+ new bioengineering companies in the past five years. The average number of employees is about 16 people.
- 10 Top Bioengineering Companies to Watch:
- Aopia Biosciences – Bio-nanoparticles Purification
- IntraClear Biologics – Age-related Diseases Therapies
- Nanocarry Therapeutics – Brain Cancer & CNS Therapeutics
- DeepLife – Deep Learning-based Cell Modeling
- Myria Biosciences – Therapeutic Molecules Creation
- Ex Planta – Biosynthetic Isoflavonoids
- Avery Digital – Full-Stack High Throughput Platform
- twig – Sustainable Consumer Goods Ingredients
- Zero Cow Factory – Animal-free Dairy Products
- Kintsugi Therapeutics – Endoplasmic Reticulum Stress Inhibitor
Meet 10 out of 800+ Emerging Bioengineering Companies
In this section, we showcase a handpicked list of 10 new bioengineering companies that are innovating in various therapeutic domains. These companies utilize several approaches like targeting endoplasmic reticulum stress to develop novel therapeutics, or bio-nanoparticle purification techniques that enhance the delivery and efficacy of drugs. They integrate biotechnologies to create solutions that impact healthcare outcomes.
Note on Signal Strength
One of the unique metrics we feature for each company is Signal Strength, a proprietary data point generated by our Discovery Platform. It gauges the extent to which a company’s influence has permeated the global ecosystem of startups, scaleups, and emerging companies. This proprietary metric serves as a valuable guidepost for understanding a company’s standing in the broader market landscape.
1. Aopia Biosciences
- Founding Year: 2019
- Employee Range: 2-10
- Location: USA
- Signal Strength: Strong
- What they do: Aopia Biosciences purifies bio-nanoparticles for biomedical applications. The company’s NanoEX, an exosome isolation platform, features automated processing and recovery rates for protein removal. Aopia Biosciences also offers the VanoFlow EV Isolation Cassette, for high-throughput and fully enclosed processing to prevent cross-contamination. The asymmetric nanopore membrane (ANM) and magnetic nanopore membrane (MNM) technologies drive these platforms to provide high yield, purity, and specific EV population isolation. These solutions together assist in disease diagnostics and therapeutic development.
2. IntraClear Biologics
- Founding Year: 2020
- Employee Range: 2-10
- Location: Estonia
- Signal Strength: Medium
- What they do: IntraClear Biologics develops therapies targeting the molecular and cellular damage that causes age-related diseases. These therapies include addressing the buildup of lipofuscin and 7-ketocholesterol (7KC), substances linked to cellular aging and age-related diseases. They target these accumulations to mitigate the effects of aging on the brain and muscles to reduce the incidence of neurodegenerative and neuromuscular diseases. These therapies also reduce chronic inflammation and prevent conditions such as Alzheimer’s and Parkinson’s diseases.
3. Nanocarry Therapeutics
- Founding Year: 2021
- Employee Range: 2-10
- Location: Israel
- Signal Strength: Very Strong
- What they do: Nanocarry develops therapeutics for brain cancers and central nervous system (CNS) diseases using its AxS drug delivery platform based on bioengineered gold nanoparticles. This platform overcomes the blood-brain barrier (BBB) crossing to increase brain delivery of therapeutic agents. AxS combines receptor-mediated transcytosis (RMT) with gold nanoparticles (GNP) to target specific brain regions for treating neurological conditions. The technology supports a plug-and-play approach to developing brain therapeutics, from antibodies to peptides. It enables effective delivery with enhanced pharmacokinetics to reduce off-target effects and improve drug stability.
4. DeepLife
- Founding Year: 2019
- Employee Range: 2-10
- Location: France
- Signal Strength: Very Strong
- What they do: DeepLife uses deep learning to model cells and engineer their behavior for offering digital twins from in vitro to in silico environments. The company’s platform integrates multi-omics data, machine learning, and systems engineering to pinpoint molecular triggers for restoring cell health. DeepLife Datastore, a multi-omics database draws data from repositories for drug discovery. DeepLife Analysis, a data analysis workflow, utilizes flexible R and Python toolboxes for advanced computational workflows. Additionally, DeepLife Virtual Cell, an AI for system biology, uses interpretable AI to identify druggable targets and conduct comprehensive pathway analysis. These solutions assist pharmaceutical companies, academics, and biotechs in accelerating drug discovery through AI.
5. Myria Biosciences
- Founding Year: 2022
- Employee Range: 2-10
- Location: Switzerland
- Signal Strength: Strong
- What they do: Myria Biosciences creates therapeutic molecules by blending small molecules and biologics. It utilizes genetically engineered modular molecule scaffolds (GEMMS) with modular DNA from nonribosomal peptide synthetases (NRPS) and polyketide synthases (PKS). These modules recombine to produce functional molecules for pharmaceutical applications. The process includes high-throughput production and in vivo testing, with iterative structure-activity relationship analysis to refine drug candidates. This methodology assists in multi-site and bi-specific binding and reaches intracellular targets. It also blocks macromolecule interactions to allow cavity binding.
6. Ex Planta
- Founding Year: 2020
- Employee Range: 2-10
- Location: Australia
- Signal Strength: Medium Strong
- What they do: Ex Planta produces biosynthetic isoflavonoids using yeast fermentation. The company utilizes advanced tools such as 3D Genomics, sequencing, clustered regularly interspaced short palindromic repeats (CRISPR) genome editing, and computing. Specifically, Ex Planta’s process synthesizes isoflavonoids like daidzein, genistein, formononetin, and biochanin-A associated with cancer, migraine, menopause syndrome, hypertension, diabetes, and chronic diseases. Thus, the company’s solution finds applications in the nutritional, cosmetics, and medicinal industries.
7. Avery Digital
- Founding Year: 2020
- Employee Range: 2-10
- Location: USA
- Signal Strength: Very Strong
- What they do: Avery Digital develops a full-stack high-throughput platform using AI and complementary metal-oxide-semiconductor (CMOS) chip technology. The platform constructs and analyzes precision genetic variants rapidly. Additionally, Avery Digital’s platform synthesizes and activates complex DNA sequences, from oligos to chromosomes, in both cellular and cell-free systems. This accelerates the discovery, optimization, and scaling of bioengineering processes.
8. twig
- Founding Year: 2022
- Employee Range: 2-10
- Location: UK
- Signal Strength: Very Strong
- What they do: twig’s AI-driven bioengineering process develops sustainable consumer goods ingredients. The company’s tool, Bio:Builder, constructs a library of DNA parts for stabilized strains for continuous fermentation processes. Grow:Bot, the company’s robotic system manipulates and analyzes bacterial variations for the ML:Bridge engine. ML:Bridge acts as the analytical unit that provides real-time feedback and insights from continuous experimentation to optimize the bioengineering workflow. twig’s solutions thus save time and reduce risk with sustainable ingredients using machine learning.
9. Zero Cow Factory
- Founding Year: 2020
- Employee Range: 11-50
- Location: India
- Signal Strength: Very Strong
- What they do: Zero Cow Factory produces animal-free milk protein and dairy products using bioengineered microbes and precision fermentation. This approach utilizes microorganisms, such as yeast, to synthesize milk proteins by removing animal involvement. The products result in zero lactose, cholesterol, saturated fats, antibiotics, and growth hormones. This method includes reduced land, water, and energy consumption, and lower CO2e emissions to support sustainability.
10. Kintsugi Therapeutics
- Founding Year: 2019
- Employee Range: 2-10
- Location: Spain
- Signal Strength: Very Strong
- What they do: Kintsugi Therapeutics develops therapies that regulate endoplasmic reticulum stress to treat liver diseases. The company targets conditions like non-alcoholic steatohepatitis (NASH), inflammation, and liver damage. NASH develops as a subgroup of non-alcoholic fatty liver disease (NAFLD) characterized by steatosis (fatty liver).
Quick Tip to Find New Bioengineering Companies
Utilizing a SaaS platform like the Discovery Platform for identifying new bioengineering companies provides significant benefits compared to traditional scouting methods:
- Streamlined Efficiency: The Discovery Platform offers advanced tools that streamline the scouting process. It replaces your hours of conventional desk research, saving time and resources in identifying bioengineering innovations.
- Access to Real-time Insights: Gain a competitive edge with up-to-date information on the latest trends in the bioengineering industry. The platform keeps you informed with near real-time updates on emerging bioengineering companies and news, enabling you to make swift and informed decisions.
- Tailored Exploration: Customize your search to focus on specific niches within the bioengineering sector, such as bio-nanoparticle purification, biosynthetic isoflavonoids, or age-related disease therapies. The platform’s diverse filtering options allow you to target your scouting efforts precisely, ensuring that you find the most relevant and groundbreaking companies in the field.
Ready to Explore All New Bioengineering Companies?
We’ve explored the dynamic landscape of the bioengineering industry, examining the latest trends and spotlighting exceptional companies driving innovation. To dive deeper, download our free BioTech Report or schedule a demo of the Discovery Platform for a customized exploration of these groundbreaking developments. Interested in contributing your expertise on startups and tech? We’d love to hear from you.
