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Discover 5 Top BioTech Startups working on Epigenomics

Curious about new technological advancements in the BioTech industry? Explore our analysis of 170 global epigenomics startups & scaleups and learn how their solutions impact your business!

Staying ahead of the technology curve means strengthening your competitive advantage. That is why we give you data-driven innovation insights into the BioTech industry. This time, you get to discover 5 hand-picked epigenomics startups.

Global Startup Heat Map highlights 5 Top Epigenomics Startups out of 170

The insights of this data-driven analysis are derived from the Big Data & Artificial Intelligence-powered StartUs Insights Discovery Platform, covering 2.093.000+ startups & scaleups globally. The platform gives you an exhaustive overview of emerging technologies & relevant startups within a specific field in just a few clicks.

The Global Startup Heat Map below reveals the distribution of the 170 exemplary startups & scaleups we analyzed for this research. Further, it highlights 5 epigenomics startups that we hand-picked based on criteria such as founding year, location, funding raised, and more. You get to explore the solutions of these 5 startups & scaleups in this report. For insights on the other 165 epigenomics solutions, get in touch.

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EpiQMAx offers Histone Modification Assays

Histone modifications are epigenetic markers linked to disease development and progression in cancers. Quantifying histone modifications is, therefore, crucial to understanding their molecular role in diseases. This is why biotech startups are developing histone modification assays for use in biotech, pharma, and healthcare. These solutions quantify levels of a large number of histone modifications across cells to present a global picture of changes in gene expression.

EpiQMAx is a German startup that provides histone modification assays. The startup’s solution simultaneously measures up to 80 histone modifications. The test has high sensitivity and works with even low sample volumes. The startup’s services include validating antibody targets, assessing epidrug efficacy, and other custom epigenomics solutions to quantify epigenomics role in diet or health.

EpigenCare develops Personal Epigenomics Testing

Skincare products that work for some often show no benefit for others. People later blame these differences on genetics. However, it is mostly due to epigenetic changes that have long-lasting effects on a person’s health. Epigenomics underlines how two people – even identical twins – react differently to different products. This is why biotech startups offer personal epigenomics tests to produce individual epigenetic profiles.

US-based startup EpigenCare develops a personal epigenomics test. SKINTELLI is a consumer biotech product that measures DNA methylation levels of genes that control aging, elasticity, moisture retention, and other factors of skin health. The startup’s kit uses non-invasive adhesives to collect skin samples that are sent to a lab for sequencing. EpigenCare then recommends skincare products that best match each person’s skin.

genknowme advances Preventive Medicine

Lifestyle and environmental factors, such as poor diet or pollution, alter epigenetic patterns in cells. Consequently, this often leads to large disparities in a person’s chronological and biological ages. To quantify this, startups offer epigenomics solutions to measure the impact of external factors on a person’s health. Compared to genomics solutions alone, such approaches provide deeper insights into susceptibility to diseases.

Swiss startup genknowme advances epigenetic testing for preventive medicine. The startup’s test performs an epigenetic assessment on blood samples to determine a patient’s biological age. It then delivers an epigenetic profile that quantifies the impact of environment and lifestyle on DNA. This enables preventive medicine and helps increase longevity.

Epify develops Epigenetic Biomarkers

Epigenetic changes generally provide rich information into the function of genes. To leverage this, startups are developing epigenetic modulators as biomarkers. These help researchers understand the link between environment and health, as well as monitor the effect of therapies on different patients. Startups use epigenomics approaches to find novel, better epigenetic biomarkers for multi-target assays.

Epify is a Dutch startup developing epigenetic biomarkers for cancer diagnosis. The startup’s solutions detect different kinds of epigenetic modifications, including DNA methylations, histone modifications, and RNA transcript modifications. It helps companies set up their biomarker discovery pipelines, or use Epify’s biomarkers, to develop their diagnostic tests. Moreover, it also aids the development of clinical practices that leverage epigenomics.

Epigeneron provides Epigenetic Drug Discovery

Many diseases such as cancers, central nervous system (CNS) disorders, and fibrosis are linked to abnormal gene expression. While previously intractable, developments in epigenomics allow researchers to explore these mechanisms. As a result, pharma startups are now increasingly focusing on epigenetic drug discovery. These drugs generally target and inhibit particular epigenetic regulators.

Japanese startup Epigeneron provides epigenetic drug discovery. The startup uses the locus-specific chromatin immunoprecipitation (ChIP) method to find gene-specific epigenetic regulators. It also identifies genes that contribute to pathological expression in diseases. The startup contracts its services to other pharma companies in addition to developing its in-house portfolio.

Discover more BioTech Startups

Epigenomics startups, such as the examples highlighted in this, report focus on biomarkers and drug discovery, as well as preventive medicine and testing molecular assays. While all of these technologies play a major role in advancing biotechnology, they only represent the tip of the iceberg. To explore more gene-based technologies, simply get in touch to let us look into your areas of interest. For a more general overview, you can download our free BioTech Innovation Report to save your time and improve strategic decision-making.

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