Staying ahead of the technology curve means strengthening your competitive advantage. That is why we give you data-driven innovation insights into the BioTech industry. This time, you get to discover 5 hand-picked biomanufacturing startups.
Global Startup Heat Map highlights 5 Top Biomanufacturing Startups out of 436
The insights of this data-driven analysis are derived from the Big Data & Artificial Intelligence-powered StartUs Insights Discovery Platform, covering 1.379.000+ startups & scaleups globally. The platform gives you an exhaustive overview of emerging technologies & relevant startups within a specific field in just a few clicks.
The Global Startup Heat Map below reveals the distribution of the 436 exemplary startups & scaleups we analyzed for this research. Further, it highlights 5 Biomanufacturing startups that we hand-picked based on criteria such as founding year, location, funding raised, and more. You get to explore the solutions of these 5 startups & scaleups in this report. For insights on the other 431 biomanufacturing solutions, get in touch.
64xBio improves Cell Line Engineering
Biomanufacturing is moving beyond growing products in bacterial or yeast cells. Cell line engineering is enabling scalable biomanufacturing of pharmaceutical products. For instance, gene therapy is on the rise, with startups even offering off-the-shelf therapies. To this end, BioTech startups develop new technologies for biomanufacturing viral vectors.
64x Bio is a US-based startup developing enhanced cell lines for biomanufacturing. The startup’s VectorSelect platform combines deoxyribonucleic acid (DNA) synthesis, next-generation sequencing (NGS), and machine learning to discover highly productive cell lines. It uses a proprietary genetic barcoding method for massively parallel screening of millions of candidate cell lines. The startup’s cell lines enable the manufacturing of viral vectors for cell and gene therapies.
C3 BIOTECH manufactures Aviation Biofuel
The BioTech industry offers biofuels as a sustainable alternative to fossil fuels. For instance, the aviation sector seeks to blend aviation biofuels with jet fuel to lower its carbon emissions. However, growing plants for biofuel production takes land away from food production. This is why BioTech startups are developing technologies to derive biofuels from agricultural and food waste.
British startup C3 BIOTECH develops new biomanufacturing solutions for aviation fuel precursors. The startup’s proprietary technologies convert agricultural, food, and industrial waste into BIO-AIR, aviation biofuel, as well as bio-liquefied petroleum gas (BioLPG). The adaptability of the process ensures that the product meets the feedstock and BioLPG composition requirements of different countries. The startup uses both fermentation and photocatalysis methods to produce BioLPG, as well as manufactures bioethanol via photocatalytic technologies.
Future Fields enables Cellular Agriculture
Cellular agriculture offers an animal-free alternative to animal products, lowering emissions from livestock. By decoupling food production with land use, it overcomes many other challenges involved in the agriculture sector. This is why biomanufacturing startups are developing novel formulations to advance cellular agriculture. For instance, using serum-free media improves reproducibility and makes downstream processing easier.
Canadian startup Future Fields provides customized growth media for cellular agriculture. It provides cost-effective and scalable growth media for the production of cultured meat and milk. Future Fields offers serum-free formulations that contain all the growth factors and other key components necessary to the growth of cell lines in culture. The startup uses a novel platform to produce bioactive growth factors that provide robust cell growth while reducing the cost of media.
Biotic develops Bioplastics
Only a small fraction of plastics are recycled, with most of them finding their way to oceans and other ecosystems. As consumer acceptability of plastics drops, startups are developing more sustainable and eco-friendly alternatives. BioTech startups leverage biomanufacturing to produce bioplastic polymers. These utilize biomass feedstocks, agricultural byproducts, and used plastics as sources and reduce energy costs for manufacturers.
Biotic is an Israeli startup that manufactures fully bio-based and biodegradable polymers. The startup utilizes sea algae and continuous production processes to create a bioplastic. In addition to providing a sustainable alternative to plastics, the startup’s solution reduces greenhouse emissions and rehabilitates marine biodiversity.
Debut Biotechnology works on Cell-Free Biomanufacturing
Growing proteins like human insulin in microbial cells is tricky, as the yield is reduced by microbes using energy to grow instead. This limits their viability, presenting a long-standing limitation to biomanufacturing technologies. Cell-free biomanufacturing harvests the cellular machinery, using it to manufacture proteins of interest. This enables higher production rates as well as shorter development times.
US-based startup Debut Biotechnology provides solutions for cell-free biomanufacturing. The startup creates better enzymes for pharmaceutical production via directed evolution. It uses patented approaches to immobilize evolved enzymes and whole cells. Lastly, the startup also offers plug-and-play cartridges with these immobilized on them for continuous fermentation.
Discover more BioTech Startups
BioTech startups such as the examples highlighted in this report focus on gene editing, tissue engineering, artificial intelligence as well as microfluidics. While all of these technologies play a major role in advancing the BioTech sector, they only represent the tip of the iceberg. To explore more technologies, simply get in touch to let us look into your areas of interest. For a more general overview, you can download our free BioTech Innovation Report to save your time and improve strategic decision-making.